SORNAVALLI VALLIAPPAN,SUBASH MOHAN THULASI,NIMITHAP SAM ALEX,SAI SINDHURI MARUVADA,GOWRI SHANKAR,SHRUTHI MANOHARAN
DOI: https://doi.org/Background: Catheter-related bloodstream infections (CRBSIs) represent a critical concern in dialysis patients, particularly those reliant on central venous catheters for vascular access, and are a leading cause of morbidity and mortality. It is necessary for each hospital to conduct a microbiological profiling of CRBSI to identify the specific organisms in that patient population, determine the antibiotic resistance patterns and improve patient outcomes through tailored interventions.
Methods: We identified 45 patients with catheter-related blood stream infection. Clinical data was obtained through review of medical records. The data reported here are those available from October 2023 to March 2024. The objective of this study is to study the microbiological profile of dialysis patients with CRBSI in our tertiary care hospital.
Results: We identified 45 dialysis patients afflicted with catheter-related blood stream infection. 20 (44.44%) patients had probable CRBSI, 15 (33.33%) patients had possible CRBSI, 10 (22.22%) patients had definite CRBSI. 17 (37.7%) catheters were salvaged. Gram positive organisms were more frequently implicated, with methicillin resistant staphylococcus aureus being the most common organism grown in culture. Antibiograms were analysed in culture-positive probable and definite CRBSI.
Conclusion: CRBSI causal organisms found in our research population may differ from those found in other centres, thus highlighting the importance of each centre studying its microbiological spectrum and modifying empirical antibiotics accordingly. According to our study, the most common organism involved in CRBSI is MRSA. Analysis of antibiogram suggests using Vancomycin and Meropenem as empirical antibiotics, preferred over ceftazidime.
Categories: Internal Medicine, Nephrology
