DR. LALITHAA J,DR. SUDHA V
DOI: https://doi.org/Peripheral blood smear analysis has long been regarded as an essential component of hematological diagnostics, playing a critical role in identifying and monitoring a diverse range of blood disorders. These disorders range from anemia and infections to more severe conditions like leukemia and other hematologic malignancies. Accurate interpretation of blood smears relies heavily on the quality and consistency of the smear preparation process, which has historically been manual, labor-intensive, and prone to variability. Despite the pivotal role of peripheral blood smears in diagnostics, traditional preparation methods often face challenges. Creating a blood smear manually involves a technician spreading a droplet of blood across a slide to form a thin film, a process that requires precision and skill to ensure optimal results. This process, while seemingly straightforward, is subject to significant variability based on the technique and expertise of the operator. Such inconsistencies can lead to sub optimal smear quality, potentially compromising diagnostic accuracy. Studies have shown that poorly prepared smears may obscure critical morphological details, leading to diagnostic errors and delays in clinical decision-making.[1,2]