NARGIZA NURILLAEVA,HAYDER MUHAMED ABAS,AZIMJANOV NAZIRBEK,RAMESH BALASUBRAMANIAN ,MR. VENU ANAND DAS VAISHNAV
DOI: https://doi.org/Today, the majority of medications used to treat illnesses are natural compounds. Marine creatures, which offer enormous potential as a source of novel active chemicals, have been the subject of study that began with terrestrial organisms. Gorgonian octocorals are a well-known source of naturally occurring bioactive substances among marine organisms. Often present in octocorals, the diterpenes are a class of chemicals having a variety of biological actions, such as antibacterial, antiviral, antifungal, anticancer, anti-inflammatory, and antiprotozoal properties. The pseudopteranes, a family of about 30 diterpenes, are a special kind of diterpene that is only found in marine environments. Despite being common, nothing is known about the biological actions of the majority of these diterpenes. Though newer marine molecules do harbor many with very impressive biological activity, setting up definite mechanisms of action is not easy. Most marine natural products research inclines to determine activity against one specific target only. These approaches do not guarantee any target discovered to be the sole, or even the primary, mediator of the biological activity and only occasionally compounds are probed to an extent sufficient to elucidate the mechanisms of action of marine natural products or their analogues. Here, we outline the anti-inflammatory properties of variously structured diterpene molecules.
