MOHAMMAD SALEH ALSAEED, PT, OMTC, ISMAIL ABDU ABU SHAMLA ,PT, ABDULRAHMAN RAJEH ALBOGAMI, ABDALAZIZ OSAMA MASOUD, PT, KHALID FARIS ALARAWI PT, ,IBRAHIM EISSA J ALFAIFI, AHMED ABDULLAH ALJOHANI, PT, OMTC, DN, RENAD SULAIMAN ALJOHANI, PT., LAMA SALEH ALAHMADI, PT, OMTC, SHARIFA HUSSEIN ABUAWJAA , RN, FAHAD ABDULRAHMAN ALBAHELI, PT

DOI: https://doi.org/

Background: Anterior cruciate ligament (ACL) injuries are prevalent in athletes and lead to significant neuromuscular and functional deficits. Conventional rehabilitation has limitations that may be addressed by robotic-assisted therapies.

Objective: This systematic review aims to evaluate the effectiveness of robotic rehabilitation interventions in improving neuromuscular control, functional outcomes, and recovery trajectories following ACL injury or reconstruction.

Methods: A comprehensive literature search was performed across multiple databases following PRISMA guidelines, including randomized controlled trials, cohort studies, and narrative reviews from 2000–2025 focusing on robotic rehabilitation post-ACL injury.

Results: Robotic rehabilitation showed consistent benefits in quadriceps strength, neuromuscular activation, proprioception, and balance compared to traditional methods. Integrative approaches combining robotics with neuromuscular electrical stimulation and virtual reality demonstrated enhanced functional recovery and neuroplasticity.

Conclusion: Robotic rehabilitation represents a promising advancement in ACL recovery, improving both peripheral muscle function and central nervous system adaptations. Future research should address optimization and personalization of robotic protocols for long-term outcomes.