PATTERN OF LIPID PROFILE LEVELS IN DIABETIC PATIENTS PRESENTING IN TERTIARY CARE HOSPITAL

MARYAM FAROOQ, PROF BRIG (R) MUHAMMED TAHIR, MUHAMMAD NAVEED, SHAFIA MANAN, MAHNOOR BABER, MUHAMMAD MUJTABA SHAHID BAIG, DR. MAHWISH ASHRAF

Background: Diabetes mellitus (DM) is a significant global population health concern that is associated with metabolic imbalance (carbohydrates, lipids, and proteins) caused by insulin resistance and/or deficiency. Dyslipidemia is another frequent comorbid condition of type 2 diabetes mellitus (T2DM) that leads to cardiovascular morbidity and mortality.

Objective: The purpose of this study is to determine the mean lipid profile values in patients with diabetes mellitus, presenting to Punjab Rangers Teaching Hospital, Lahore.

Methodology: The study was a  cross-sectional one carried out at the Department of Medicine, Punjab Rangers Teaching Hospital, Lahore from July 2025 to October 2025. Non-probability consecutive sampling was used to enroll 300 patients diagnosed with T2DM who were aged between 18 and 50 years. Comorbidities (hypertension, chronic liver disease, long-term drug use) were excluded. Triglycerides (TG), total cholesterol (TC), high-density lipoprotein (HDL-C) and low-density lipoprotein (LDL-C) levels in blood were assessed. The analysis of the data was performed with SPSS v 28.

Results: The mean triglyceride level was 168.45±82.13 mg/dL, total cholesterol 182.76±44.92 mg/dL, HDL-C 42.67±10.85 mg/dL, and LDL-C 118.32±34.56 mg/dL. A large percentage of patients had dyslipidemia, with the most frequent abnormalities being increased TG and decreased HDL-C.

Conclusion: Diabetic patients had a high-frequency of dyslipidemia, especially high triglycerides and low levels of HDL. The findings reveal the importance of screening and treating lipid abnormalities at an early stage and managing it aggressively to minimize the risks of cardiovascular conditions among diabetic populations.