DR R SOWMYA,DR SRIDEVI M,DR. GANESH RAMESH
DOI: https://doi.org/Objective:The purpose of this study is to assess the correlation and accuracy of Pap smears in the diagnosis of cervical lesions by comparing cytological findings with histopathological test results.
Introduction:Cervical cancer is an important issue in public health, especially in developing countries. Early detection by screening programs is extremely important to reduce morbidity and mortality. PAP smears are often used as the primary screening tool for cervical cancer. However, accuracy and correlation with histopathological examination (HPE) should require continuous evaluation to ensure effective diagnosis and treatment. 1-5.
Materials and Methods:A prospective study was conducted, and data from patients with abnormal cervical cytology or clinically unhealthy cervix were analyzed. Pap smear samples were collected and evaluated using the Bethesda System for Reporting Cervical Cytology. Subsequently, cervical biopsies were performed on patients with abnormal Pap smear results. Histopathological examination (HPE) was conducted on biopsy samples to confirm the diagnosis.
Statistical Analysis:
The correlation between Pap smear results and histopathological diagnoses was assessed. Chi-square tests were used to determine the level of correlation. Sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of the Pap smear were calculated with histopathological findings as the gold standard.
