DR. ANUSUYA C,PROF. DR. KHALILUR RAHMAN,DR. RAHUL RAJ,DR. DAKSHAY CHORDIA,DR.V. RAMYA
DOI: https://doi.org/Background: The coexistence of autoimmune disorders such as Sjögren’s syndrome (SS) and infectious diseases like tuberculosis (TB) poses significant diagnostic and therapeutic challenges, especially in TB-endemic regions. Immunosuppressive therapy for SS increases TB reactivation risk, complicating management strategies.
Case Presentation: A 45-year-old female with SS presented with progressive lower abdominal pain. Imaging suggested appendicular inflammation; however, laparoscopy revealed an ileocaecal mass. Limited resection of the terminal ileum and proximal ascending colon was performed. Histopathology confirmed ileocaecal TB. The patient received anti-tubercular therapy alongside adjusted immunosuppressive treatment under multidisciplinary care.
Conclusion: This case underscores the importance of comprehensive screening for latent TB before immunosuppressive therapy, individualized perioperative immuno suppressive management, and multidisciplinary coordination in patients with overlapping autoimmune and infectious diseases.
