ARAVIND. K,AJAY KUMAR. A,DR. SAJID .T HUSSAIN
DOI: https://doi.org/Superficial angiomyxoma (SAM) represents an uncommon benign mesenchymal tumor of cutaneous origin, with only sporadic cases reported in the genital region. This article presents a detailed case study of a 35-year-old female who developed a slow-growing, asymptomatic mass on the left labia majora over a one-year period. The clinical presentation, diagnostic workup, surgical management, and histopathological findings are comprehensively described. Microscopic examination revealed characteristic features of SAM, including a well-demarcated lesion composed of myxoid stroma with prominent vascular components and scattered adipocytes, without evidence of cellular atypia. The patient underwent complete surgical excision with no signs of recurrence at six-month follow-up. This case underscores the diagnostic challenges posed by vulvar SAM due to its clinical similarity to more common labial lesions and emphasizes the critical role of histopathological examination in establishing a definitive diagnosis. The discussion incorporates a thorough review of current literature regarding the epidemiology, pathological characteristics, immunohistochemical profile, and management strategies for SAM, with particular attention to its differentiation from morphologically similar entities such as aggressive angiomyxoma.
